Research in many fields confirms that science is changing its nature. Natural science, cognitive and social sciences, mathematics and philosophy (i.e., the set of tools developed to understand and model reality) exceed the conceptual framework introduced by Galileo and Descartes. Complexity and chaos; network dynamics; anticipatory systems; qualitative aspects of experience (intentionality, for example); emergent properties and objects; forward, upward, and downward causation: all portend a new scientific agenda.